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Situated amidst the lush landscapes of Panama, the vibrant city of Panama City serves as the gateway to remarkable adventures and unforgettable experiences in this captivating country. With its modern infrastructure and well-connected transportation network, Panama City offers convenient access to the diverse natural wonders and wildlife-rich destinations that Panama is renowned for.


Flights from Europe


Flights from North America


Flights from South America




Panama City is a vibrant and dynamic city located at the Pacific entrance of the Panama Canal. Nestled between the stunning Pacific coastline and lush rainforests, it offers a unique blend of natural beauty, modern architecture, and rich history.

The city is known for its impressive skyline, featuring towering skyscrapers that reflect its growing status as a financial and commercial hub in Central America.

Flights from Europe to Panama City

To travel from Europe to Panama City, there are several flight options available. While there are no direct flights from Europe to Panama City, most routes involve a layover in major cities such as Madrid, Amsterdam, Paris, or Frankfurt. Airlines such as Air France, KLM, Iberia, Lufthansa, and British Airways offer connecting flights from various European cities to Tocumen International Airport in Panama City.

The most common route is to fly from Europe to a connecting hub, such as Madrid or Amsterdam, and then take a connecting flight to Panama City. These flights are typically operated by major airlines and provide convenient connections for travelers.

Flights from North America to Panama City

There are convenient flight options available for traveling from North America to Panama City. If you are flying from the United States, you can choose direct flights from various cities, including Miami, Fort Lauderdale, Houston, Atlanta, and Los Angeles. Major airlines such as American Airlines, Delta Air Lines, and Copa Airlines operate regular flights between these destinations.

From Canada, you can also find direct flights to Panama City from major cities like Toronto and Montreal. Airlines such as Air Canada and Copa Airlines offer convenient connections for travelers from Canada.

Travel from South America to Panama City


The most common and convenient way is by air. Many airlines offer direct flights from major South American cities to Panama City, the capital of Panama. You can check with airlines for available routes and schedules.

Overland travel

If you prefer a more adventurous journey, you can consider traveling overland. There are bus services that connect various South American countries to Panama. However, keep in mind that this option requires multiple transfers and can be time-consuming.

By boat

Another option is to take a cruise or a ferry from certain South American ports to Panama. Cruise ships and ferries offer a scenic and leisurely way to travel, allowing you to enjoy the beautiful coastal views along the way.


Off Roads Travel Panama is your gateway to unforgettable adventures in the beautiful country of Panama. As an experienced and reliable travel agency, we specialize in providing exceptional off-road tours that allow you to explore the hidden gems and natural wonders of Panama.

Whether you are seeking thrilling jungle expeditions, cultural encounters with indigenous communities, or breathtaking encounters with wildlife, we have the expertise and knowledge to create an immersive and authentic travel experience


A trip to Panama City is fun and special. That is why you want to be as prepared as possible when you enter the country. Here you can find the information you need to know before entering Panama City.

What documents do I need to enter Panama?

You need the following documents to enter Panama City:

  • A current valid passport with a validity of 6 months.
  • Credit card/debit card.
  • Email address for affirmation.
  • Return ticket to the country of origin or the next destination to visit
  • The yellow fever vaccine is mandatory for all people traveling from Brazil, who must present the international vaccination certificate issued by ANVISA at least 10 days before arrival.

Do I need a COVID vaccine or vaccination certificate to enter Panama City?

Currently, there are no restrictions or requirements specific to COVID-19. However, in this link, you can always review updated information.

Do I need to take a PCR test before traveling to Panama City?

  • There are no country access restrictions.
  • There is no physical distance.
  • There is no request to fill out a digital form, therefore no vaccination is requested, nor a negative Covid-19 test.
  • Mask use is optional (not required).

Do I have to quarantine when I get to Panama City?

Quarantine requirements: There are no quarantine requirements.

What preventive measure should I take when planning a journey to Panama City?

Regardless of length of stay, the following vaccinations are recommended for Panama: vaccination against DTP (diphtheria, tetanus and polio) and vaccination against hepatitis A (contagious jaundice). For Panama, yellow fever vaccination is recommended for the provinces of Comarca Emberá, Darien and Kuna Yala (formerly San Blas) and for parts of the provinces of Colon and Panama that lie east of the Canal Zone. For Panama City, the Canal Zone and the San Blas Islands, yellow fever vaccination is not recommended, see yellow fever map South America.

For stays longer than three months, vaccinations are recommended for Panama against hepatitis B, rabies and, in some cases, tuberculosis. Sometimes vaccinations against these diseases are recommended for Panama for shorter stays.

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